Board-certified plastic surgeon · Ashley Howarth, MD, FACS

Free U.S. standard shipping on eligible retail orders

HSA/FSA eligibility may depend on your plan · Learn more

Complexion Clarifying Serum

$123.00

1.7 fl oz / 50 mL

A daily serum for skin that runs oily or congested. Z-SEB³™ helps minimize excess surface sebum, water-soluble salicylic acid decongests and refines the look of pores, and ZO-RRS2® soothes visible redness. A light water-gel that layers easily and, per the manufacturer, is proven to decongest skin and reduce shine in 2 weeks.

When to use

When to useMorningEvening

Routine step

Treat / serum

Best for

All skin types, especially oily and acne-prone

This brand ships only through licensed practices. Request it here and our team confirms availability and pricing, usually the same day.

Why Dr. Howarth recommends it
The serum for acne and congestion plans where a retinoid alone is too drying. It is fragrance- and alcohol-free, and ZO’s 6-week study reported decongestion without irritation in 98% of subjects.
  • Helps decongest skin and reduce shine in 2 weeks
  • Minimizes excess sebum with daily use
  • Reduces visible redness for a more uniform complexion
  • Light water-gel formula layers easily

Apply to clean, dry skin morning and night. The dropper fills automatically, so one draw is ready to apply.

  • Z-SEB³™: sebum-targeting complex that helps minimize surface oil and support a balanced microbiome
  • Water-soluble salicylic acid: decongests skin and refines the look of pores without drying
  • ZO-RRS2®: plant stem cell complex that soothes visible redness and neutralizes free radicals
Aqua/Water/Eau, Propanediol, Glycerin, Salicylic Acid, Sodium Polyacrylate, Butylene Glycol, Eugenia Uniflora Leaf Extract, Laminaria Digitata Extract, Rosa Canina Fruit Extract, Syringa Vulgaris (Lilac) Extract, Opuntia Ficus-Indica Stem Extract, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Meristem Cell Culture, Lecithin, Galactoarabinan, Schizophyllan, Maltodextrin, Caprylyl Glycol, Phytic Acid, Trisodium Ethylenediamine Disuccinate, Inulin Lauryl Carbamate, Acacia Senegal Gum, Xanthan Gum, Mannitol, Sodium Citrate, Hydroxyacetophenone, Trehalose, Sodium Bisulfite, Ergothioneine, Phenoxyethanol, Chlorphenesin, Benzyl Alcohol, Potassium Sorbate, Sodium Benzoate.

Free U.S. standard shipping on eligible retail orders; orders ship from Scottsdale within 1–2 business days. Shipping & Delivery · Returns & Refunds · Order tracking

Complexion Clarifying Serum

$123.00
1.7 fl oz / 50 mL