Board-certified plastic surgeon · Ashley Howarth, MD, FACS

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AlphaRet Overnight Cream

$210.00

1 oz / 30 mL · 1.7 oz / 50 mL

The cream built on AlphaRet® Technology, a patented molecule that joins a retinoid to an alpha hydroxy acid for overnight skin renewal that stays tolerable. Glycolic acid helps retexturize, a peptide blend helps smooth the look of wrinkles, and ceramides, squalane, niacinamide and hyaluronic acid counter the dryness retinoids can bring. Dispensed from an airless pump.

When to use

When to useEvening

Routine step

Treat / retinoid

Best for

All skin types, including retinoid-sensitive

This brand ships only through licensed practices. Request it here and our team confirms availability and pricing, usually the same day.

Why Dr. Howarth recommends it
The retinoid on Dr. Howarth’s shelf for most skin, including skin that has not tolerated retinoids before. It was tested in retinoid-sensitive users for nightly use, and Skinbetter Science supplies it only through licensed practices, so it comes with a clinician’s guidance rather than a shelf tag.
  • Improves the appearance of fine lines and wrinkles
  • Helps even the look of tone and texture
  • Hydrating blend counters retinoid dryness
  • Tested on retinoid-sensitive users for nightly use

In the evening after cleansing, apply a thin layer evenly over a clean, dry face, avoiding the eye area, then follow with the rest of your evening routine. It is designed for nightly use; if skin is new to retinoids, begin with 2–3 nights a week and build up. Wear sunscreen during the day, as the AHA may increase sun sensitivity while using and for a week afterward. Contains a topical retinoid; if pregnant, nursing or planning to become pregnant, consult a physician before use, and using more than one exfoliating product may cause irritation.

  • AlphaRet® Technology: patented combination of a retinoid and lactic acid in one molecule
  • Glycolic acid: helps retexturize and supports the performance of AlphaRet
  • Ceramides, squalane, niacinamide and hyaluronic acid: hydrating blend that helps counter dryness
Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891)

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AlphaRet Overnight Cream

$210.00
1 oz / 30 mL · 1.7 oz / 50 mL