Board-certified plastic surgeon · Ashley Howarth, MD, FACS

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Daily Power Defense

Price range: $117.00 through $190.00

1.7 fl oz / 50 mL · 1 fl oz / 30 mL

ZO’s daily defense serum for all skin types. Vitamins A and E, ZO-RRS2® and ZPOLY™ help neutralize free radicals, soothe visible redness and support the skin barrier with extended hydration, while specialized enzymes encourage healthy skin cell function. A lightweight serum worn morning and evening.

When to use

When to useMorningEvening

Routine step

Treat / serum

Best for

All skin types

This brand ships only through licensed practices. Request it here and our team confirms availability and pricing, usually the same day.

Why Dr. Howarth recommends it
The daily anchor of a ZO regimen, the step every other ZO product is built around. In ZO’s 12-week study, 92% of subjects had healthier-looking skin by week 2, the kind of early, visible change that keeps a routine going.
  • Defends skin against oxidative damage
  • Visibly reduces signs of premature aging
  • Supports barrier restoration and extended hydration
  • Supports continuously healthy skin

Apply to clean, dry skin morning and evening. ZO’s program guidance is 2–3 pumps over the entire face and neck.

  • Vitamins A and E: antioxidants that help protect against environmental skin aging
  • ZO-RRS2®: plant stem cell complex that neutralizes free radicals and soothes visible redness
  • ZPOLY™: plant-derived polysaccharide complex that minimizes premature aging signs and extends hydration
Aqua/Water/Eau, Dicaprylyl Carbonate, Cetearyl Isononanoate, Glycerin, Pentylene Glycol, Cetearyl Alcohol, Steareth-20, Safflower Oil/Palm Oil Aminopropanediol Esters, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Arabidopsis Thaliana Extract, Marrubium Vulgare Meristem Cell Culture, Leontopodium Alpinum Meristem Cell Culture, Retinyl Palmitate, Tocopheryl Acetate, Tocopherol, Micrococcus Lysate, Caprylyl Glycol, Hexylene Glycol, Lactose, Galactoarabinan, Lecithin, Schizophyllan, Beta-Glucan, 1,2-Hexanediol, Carbomer, Cellulose, Maltodextrin, C14-22 Alcohols, Cetearyl Glucoside, C12-20 Alkyl Glucoside, Hydroxypropyl Methylcellulose, Disodium EDTA, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Fragrance/Parfum, Ultramarines (CI77007), Limonene.

Free U.S. standard shipping on eligible retail orders; orders ship from Scottsdale within 1–2 business days. Shipping & Delivery · Returns & Refunds · Order tracking

Daily Power Defense

Price range: $117.00 through $190.00
1.7 fl oz / 50 mL · 1 fl oz / 30 mL