Board-certified plastic surgeon · Ashley Howarth, MD, FACS
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$53.00 – $105.00Price range: $53.00 through $105.00
The blending step in ZO’s physician-dispensed pigment programs (Rx only). Hydroquinone 4%, which ZO calls the optimal concentration for melanin inhibition, produces gradual, reversible lightening of chloasma, melasma, freckles and age spots. An emollient base distinguishes it from Pigment Control Crème, and it is applied thinly to affected areas twice daily as your physician directs.
When to use
Routine step
Best for
This brand ships only through licensed practices. Request it here and our team confirms availability and pricing, usually the same day.
Apply 2 pumps (about 1 g) as a thin application to affected areas twice a day, or as directed by your physician, and always use sunscreen; the product label says if it should be rubbed in. Reassess with your provider at 8–12 weeks if there is no improvement; not for use under 12 or during pregnancy without medical advice; patch test on an unbroken area first and check within 24 hours; avoid the eyes and discontinue if irritation develops.
Free U.S. standard shipping on eligible retail orders; orders ship from Scottsdale within 1–2 business days. Shipping & Delivery · Returns & Refunds · Order tracking
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